FLAVONOL GLYCOSIDES FROM THE NATIVE AMERICAN PLANT GAURA LONGIFLORA.

Area of Science:

• Phytochemistry
• Natural Products Chemistry
• Plant Sciences

Background:

• Gaura longiflora is a native American plant species.
• Flavonol glycosides are a class of plant secondary metabolites with diverse biological activities.

Purpose of the Study:

• To conduct a phytochemical investigation of Gaura longiflora.
• To isolate and characterize novel compounds from the plant.

Main Methods:

• Phytochemical analysis of Gaura longiflora.
• Isolation of compounds using chromatographic techniques.
• Structure elucidation using spectroscopic data (NMR, MS).

Main Results:

• Isolation of eleven flavonol glycosides, including three new compounds.
• Characterization of the new compounds: quercetin 3-O-(2″-O-α-l-rhamnopyranosyl-6″-O-E-p-coumaroyl)-β-D-glucopyranoside (1), kaempferol 3-O-(2″-O-α-l-rhamnopyranosyl-6″-O-E-p-coumaroyl)-β-d-glucopyranoside (2), and quercetin 3-O-(2″-O-α-l-rhamnopyranosyl-6″-O-Z-p-coumaroyl)-β-D-glucopyranoside (3).
• Identification of eight known flavonol glycosides.

Conclusions:

• The phytochemical investigation of Gaura longiflora yielded a diverse array of flavonol glycosides.
• The structural elucidation of the new compounds expands the knowledge of natural products from this plant genus.