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Updated: May 4, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
[Effect of compression therapy in the management of venous ulcer - practical experience]
Ivana Vranjković1, Nevenka Strok2, Zeljka Topolovec2
1Ordinacija za kozne bolesti Prim. mr sc. dr. Zeljko Pavicić. ivanavranjkovic5@yahoo.com
Insights
Venous insufficiency commonly causes chronic wounds, with venous ulcers being a major issue. These ulcers often require over a year of treatment, impacting quality of life and incurring significant costs.
Area of Science:
- Vascular Medicine
- Dermatology
- Wound Care
Background:
- Venous insufficiency is a primary cause of chronic wounds.
- Venous ulcers represent approximately 75% of all leg ulcers.
- A significant portion, 50%, of venous leg ulcers necessitate prolonged treatment exceeding one year.
Observation:
- The lower third of the leg is the most frequent site for venous ulcers due to heightened venous pressure.
- Multiple venous ulcers can occur, often affecting both lower legs.
- These ulcers severely diminish patients' quality of life through immobility, pain, and social isolation.
Findings:
- Venous ulcers are a prevalent and challenging clinical condition.
- Treatment duration for venous leg ulcers is frequently extensive, often surpassing one year.
- The condition presents substantial health, social, and economic burdens globally.
Implications:
- Effective management strategies for venous ulcers are crucial.
- Addressing the long-term treatment needs and associated costs is essential.
- Improving patient quality of life requires comprehensive care approaches for venous insufficiency and its manifestations.
Abstract:
Venous insufficiency is one of the most common causes of chronic wounds. Venous ulcers account for about 75% of all leg ulcers, and 50% of venous leg ulcers require long-term treatment lasting for more than 1 year. The most common location of venous ulcers is the lower third of the leg, as it is the site of strongest venous pressure; less often there are multiple venous ulcers that tend to be localized on both lower legs. In addition to the negative impact on the quality of life, such as immobility, pain and social isolation, which significantly affect the course and length of treatment, we cannot ignore the high costs of long-term and often uncertain treatment, which poses a major health, social and economic problem in the world and in our country.
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