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The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes

Nikolai Lorenzen1, Lasse Lemminger1, Jannik Nedergaard Pedersen1

  • 1Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus C, Denmark.

FEBS Letters
|December 31, 2013
PubMed

Keywords:
1-anilinonaphthalene-8-sulfonateA4FANSCDDLSMembrane foldingMembrane interactionOligomerPDParkinson’s DiseasePermeabilizationSDSSECThTToxicityasymmetrical flow field-flow fractionationcircular dichroismdynamic light scatteringsize exclusion chromatographysodium dodecyl sulfatethioflavin Tα-synucleinαSN

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