Related Experiment Video
Updated: May 4, 2026
09:01
An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
7.6K
Asthma and viruses: is there a relationship?
Serena Moser1, Diego G Peroni1, Pasquale Comberiati1
1Department of Pediatrics, University of Verona, Verona, Italy.
Frontiers in Bioscience (Elite Edition)
|January 7, 2014
Summary
Viral infections are a primary cause of asthma exacerbations and may contribute to asthma development. Further research is needed to confirm the causative role of viruses in asthma and develop preventive strategies for at-risk children.
Area of Science:
- Pediatric respiratory diseases
- Immunology
- Infectious diseases
Background:
- Asthma is a complex condition influenced by multiple factors.
- Viral infections are the leading trigger for asthma exacerbations.
- Evidence suggests viruses may also play a role in asthma development.
Purpose of the Study:
- To explore the role of viral infections in asthma development.
- To identify potential viral causes of asthma pathogenesis.
- To inform preventive strategies for high-risk children.
Main Methods:
- Review of existing evidence on viral infections and asthma.
- Analysis of studies linking specific viruses to asthma development.
- Identification of Respiratory Syncytial Virus (RSV) and other implicated viruses.
Main Results:
- Respiratory Syncytial Virus (RSV) is historically linked to increased asthma risk.
- Emerging evidence implicates other viruses in asthma pathogenesis.
- Viral infections are significant factors in both asthma exacerbations and potentially its development.
Conclusions:
- Viral infections are strongly associated with asthma exacerbations.
- A causative role for viruses in asthma development requires further investigation.
- Confirming viral links could lead to targeted preventive measures for pediatric asthma.
Related Concept Videos
01:28Asthma I: Introduction
112
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
112
01:29Asthma-I: Introduction
3.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
01:20Asthma: Pathogenesis and Management
1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
01:26Asthma-II: Pathophysiology and Classification
4.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.7K
01:24Asthma-III: Symptoms and Complications
3.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.5K
01:13Asthma III: Clinical Manifestations
49
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
49