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Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Intestinal tuberculosis sometimes mimics Crohn's disease.
Esfandiar Shojaei1, Zahra Abdi Layali, Sirous Faraji Hormozi
1Department of Infectious Diseasses, Tehran University of Medical Sciences, Tehran, Iran. eshojaei@sina.tums.ac.ir.
Intestinal tuberculosis mimics Crohn's disease, potentially leading to misdiagnosis. Early and thorough evaluation, including molecular tests, is crucial for accurate diagnosis and preventing disseminated disease.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Pathology
Background:
- Intestinal tuberculosis (ITB) is an uncommon form of tuberculosis (TB).
- ITB shares clinicopathological similarities with Crohn's disease (CD).
- In TB-endemic regions, clinicians must consider ITB when diagnosing CD.
Observation:
- A case is presented where intestinal tuberculosis was initially diagnosed as Crohn's disease.
- The patient developed disseminated tuberculosis after initiating immunosuppressive therapy for presumed CD.
Findings:
- Pathological evaluation of specimens is essential for diagnosing ITB.
- Microbiological tests such as smear, culture, and PCR for Mycobacterium tuberculosis aid in diagnosis.
- Effective diagnostic strategies are needed to differentiate ITB from CD.
Implications:
- Misdiagnosis of ITB as CD can lead to delayed appropriate treatment.
- Immunosuppressive therapy for misdiagnosed ITB can precipitate disseminated tuberculosis.
- Enhanced diagnostic protocols are necessary in endemic areas to improve patient outcomes.
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