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[Management of elderly onset diabetes]
Motoshi Ouchi1, Hiroshi Nakano1
1Division of Geriatric Medicine, Nippon Medical School.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|January 9, 2014
Summary
As Japan
Area of Science:
- Gerontology and Endocrinology
- Metabolic Diseases Research
Background:
- Increasing elderly population in Japan correlates with rising rates of overweight, insulin resistance, and elderly-onset diabetes.
- Elderly-onset diabetes presents unique clinical features including postprandial hyperglycemia and lower HbA1c levels.
- Management of elderly-onset diabetes is complicated by comorbidities like cognitive and functional impairments.
Purpose of the Study:
- To review the characteristics and treatment challenges of elderly-onset diabetes.
- To evaluate suitable medication options for older adults with diabetes.
- To define appropriate glycemic targets for elderly diabetic patients.
Main Methods:
- Literature review focusing on elderly-onset diabetes management.
- Analysis of treatment guidelines and clinical trial data for older adults.
- Discussion of challenges in treating diabetes in the elderly population.
Main Results:
- Elderly-onset diabetes exhibits distinct glycemic profiles and lower complication rates compared to younger onset.
- Medications requiring infrequent dosing, such as dipeptidyl peptidase 4 inhibitors, are preferred.
- Individualized hemoglobin A1c (HbA1c) targets, generally 7% to 9%, are recommended for healthy older adults.
Conclusions:
- Effective management of elderly-onset diabetes requires addressing patient-specific challenges and comorbidities.
- Dipeptidyl peptidase 4 inhibitors offer a convenient and well-tolerated treatment option for older adults.
- Individualized glycemic control is crucial for optimizing outcomes in elderly patients with diabetes.
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