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Related Experiment Video

Updated: May 4, 2026

Murine Heterotopic Heart Transplant Technique
10:27

Murine Heterotopic Heart Transplant Technique

Published on: July 8, 2014

19.7K

Fourth time cardiac retransplantation.

Hannah Copeland1, Monica Gustafson, Romana Coelho-Anderson

  • 1University of California San Diego, San Diego, CA, USA.

World Journal for Pediatric & Congenital Heart Surgery
|January 10, 2014
PubMed
Summary
This summary is machine-generated.

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A 37-year-old man remains fully active after undergoing four heart transplants starting at age 11. This case highlights the complexities and ethical considerations of multiple cardiac retransplantation.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Surgical Innovation

Background:

  • Recurrent graft failure necessitates retransplantation.
  • Multiple cardiac retransplantation is rare and technically challenging.
  • Long-term outcomes after multiple heart transplants are not well-documented.

Purpose of the Study:

  • To document a unique case of quadruple heart transplantation.
  • To explore the decision-making process for repeated cardiac retransplantation.
  • To discuss the ethical considerations surrounding multiple organ transplants.

Main Methods:

  • Case report of a patient undergoing four heart transplants.
  • Review of clinical course, surgical interventions, and outcomes.
  • Discussion of ethical frameworks and decision-making strategies.
Keywords:
failureheartheart failurekidney (includes diseaserejection (immunologic)renal function)transplantation

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Related Experiment Videos

Last Updated: May 4, 2026

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Published on: July 8, 2014

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Mouse Heterotopic Cervical Cardiac Transplantation Utilizing Vascular Cuffs
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Main Results:

  • The patient, transplanted at ages 11, 14, 18, and 22, is now 37 and fully active.
  • Successful long-term survival and functional recovery after four cardiac retransplants.
  • Demonstrates the feasibility of complex, multi-stage cardiac allograft replacement.

Conclusions:

  • Multiple cardiac retransplantation can lead to favorable long-term outcomes.
  • Careful patient selection and multidisciplinary decision-making are crucial.
  • This case provides valuable insights into managing end-stage heart failure through repeated transplantation.