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Intratarsal keratinous cyst - an emerging entity
Fatemeh Rajaii1, Abdalhossein Ghafourian1, Charles G Eberhart1
1Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Md., USA.
Case Reports in Ophthalmology
|January 10, 2014
Summary
Recurrent intratarsal keratinous cysts of the Meibomian gland are a newly identified condition. Accurate diagnosis via histopathology and cytokeratin (CK) 5/6 expression is crucial for appropriate treatment, avoiding recurrence.
Area of Science:
- Ophthalmology
- Dermatopathology
Background:
- Intratarsal cysts of the Meibomian gland are uncommon eyelid lesions.
- Previously, recurrent forms may have been misdiagnosed as other cystic conditions.
Observation:
- Two cases of recurrent intratarsal keratinous cysts of the Meibomian gland were identified.
- These lesions exhibit characteristic histopathologic features.
Findings:
- Histopathologic examination alone can establish the diagnosis.
- Cytokeratin (CK) 5/6 expression in the cyst epithelium is a specific diagnostic marker.
Implications:
- Distinguishing these recurrent cysts from non-recurrent types is essential for effective management.
- Definitive therapy requires full-thickness excision, contrasting with simple incision and drainage for other cysts.
