Luminous fabric devices for wearable low-level light therapy

Area of Science:

• Biomedical Engineering
• Materials Science
• Photomedicine

Background:

• Low-level light therapy (LLLT) is a promising therapeutic modality.
• Wearable LLLT devices require flexible, comfortable, and safe materials.
• Existing LLLT devices often lack optimal fit and long-term stability.

Purpose of the Study:

• To develop and investigate a flexible luminous fabric device for wearable, 3D-fitted LLLT.
• To evaluate the optical, thermal, and biological properties of the fabric device.
• To assess the safety of the luminous fabric for human skin contact.

Main Methods:

• Fabrication of a flexible luminous fabric device.
• Assessment of optical power density and thermal stability over 10 hours.
• In vitro study on human fibroblasts to measure collagen production.
• Skin irritation and sensitization tests according to ISO 10993-1:2003.

Main Results:

• The fabric device demonstrated stable optical power density and operating temperature for 10 hours.
• Significant increase in collagen production observed in human fibroblasts irradiated by the device.
• ISO 10993-1:2003 testing confirmed no potential hazards for direct skin contact.

Conclusions:

• The developed luminous fabric is a viable candidate for wearable LLLT applications.
• The device offers effective photobiomodulation with enhanced fibroblast collagen synthesis.
• The material is safe for prolonged and direct human skin contact, meeting international standards.