Related Experiment Video
Updated: May 4, 2026

Live Images of GLUT4 Protein Trafficking in Mouse Primary Hypothalamic Neurons Using Deconvolution Microscopy
Published on: December 7, 2017
Perineural xanthoma associated with type 2 diabetes mellitus and hyperlipidemia
Rie Arai1, Shiori Itoh, Asako Masatsugu
1Department of Dermatology, Osaka Saiseikai Izuo Hospital, Kitamura 3-4-5, Taisho-ku, Osaka 551-0032, Japan. arai88@gaia.eonet.ne.jp.
Abstract:
It is well known that patients with diabetes mellitus (DM) may demonstrate skin manifestations, or dermadromes, due to disease-related metabolic, vascular, neurologic, and/or immunologic disturbances; however, the pathogenesis of some of these manifestations remains unknown. Xanthomas often are associated with increased levels of serum cholesterol and/or triglycerides and therefore can present as a dermadrome in patients with a history of uncontrolled DM and hyperlipidemia. The presence of tender lesions in this patient population can indicate a diagnosis of perineural xanthoma. We report a case of perineural xanthoma arising in a patient with type 2 DM and hyperlipidemia.
Related Concept Videos
Type II Diabetes II: Pathophysiology
Diabetic Neuropathy
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Type I Diabetes III: Clinical Manifestations
Type II Diabetes I: Introduction
Peripheral Artery Disease I: Introduction

