Related Experiment Video
Updated: May 4, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Lidocaine: cough (fentanyl induced)
Joyce A Generali1, Dennis J Cada2
1Editor-in-Chief, Hospital Pharmacy, and Clinical Professor, Emeritus, Department of Pharmacy Practice, University of Kansas, School of Pharmacy, Kansas City/Lawrence, Kansas,
This guide aids healthcare professionals in identifying and evaluating off-label drug uses. It helps determine the rationality of unapproved drug applications in patient care scenarios using published literature.
Area of Science:
- Pharmacy
- Pharmacology
- Clinical Practice
Background:
- Off-label drug use refers to applications not approved by the US Food and Drug Administration (FDA).
- Practitioners require reliable information on these unapproved uses for informed patient care.
- Existing resources may not adequately address the need for curated literature on off-label drug applications.
Purpose of the Study:
- To introduce a practitioner-oriented resource for off-label drug information.
- To enable healthcare professionals to quickly identify relevant literature on unapproved drug uses.
- To assist clinicians in assessing the rationality of off-label drug applications in patient care.
Main Methods:
- Extraction of information from the publication 'Off-Label Drug Facts'.
- Focus on literature identifying and evaluating specific off-label drug uses.
- Provision of references for comprehensive information access.
Main Results:
- A new guide is available for healthcare professionals.
- The guide facilitates rapid identification of published studies on off-label drug uses.
- It supports the determination of whether a specific off-label use is rational.
Conclusions:
- 'Off-Label Drug Facts' serves as a valuable resource for clinicians.
- The guide enhances evidence-based decision-making for unapproved drug applications.
- It promotes rational and informed patient care concerning off-label drug use.
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