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Updated: Aug 6, 2026

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products
Published on: September 9, 2016
8-Hy-droxy-quinolin-1-ium hydrogen sulfate monohydrate
Maamar Damous1, George Dénès2, Sofiane Bouacida3
1Unité de Recherche de Chimie de l'Environnement et Moléculaire Structurale, CHEMS, Université Constantine 1, 25000, Algeria.
Abstract:
In the crystal structure of the title salt hydrate, C9H8NO(+)·HSO4 (-)·H2O, the quinoline N-H atoms are hydrogen bonded to the bis-ulfate anions. The bis-ulfate anions and water mol-ecules are linked together by O-H⋯O hydrogen-bonding inter-actions. The cations and anions form separate layers alternating along the c axis, which are linked by N-H⋯O and O-H⋯O hydrogen bonds into a two-dimensional network parallel to (100). Further O-H⋯O contacts connect these layers, forming a three-dimensional network, in which two R 4 (4)(12) rings and C 2 (2)(13) infinite chains can be identified.
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