Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

1.0K
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
1.0K
Upper Respiratory Drugs: Decongestants01:27

Upper Respiratory Drugs: Decongestants

1.4K
Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in...
1.4K
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

2.1K
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
2.1K
Epistaxis01:30

Epistaxis

857
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
857
Chronic Pharyngitis01:23

Chronic Pharyngitis

16.7K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
16.7K
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

1.6K
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"Endoscopic-assisted, subperiosteal browlift bone fixation technique outcomes: a systematic review and meta-analysis".

Plastic and reconstructive surgery·2026
Same author

Lifestyle Interventions for Major Depressive Disorder (MDD): An Expert Consensus Statement From the American College of Lifestyle Medicine.

American journal of lifestyle medicine·2026
Same author

Plant-Based Nutrition and Supplements for Optimal Athletic Performance.

American journal of lifestyle medicine·2025
Same author

Frailty and Postoperative Outcomes Following Endoscopic Endonasal Skull Base Surgery: A Scoping Review.

Ear, nose, & throat journal·2025
Same author

Guidelines Recommending That Clinicians Advise Patients on Lifestyle Changes.

Annals of internal medicine·2025
Same author

Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline From the American College of Lifestyle Medicine.

American journal of lifestyle medicine·2025

Related Experiment Video

Updated: May 3, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.8K

Topical steroid for chronic rhinosinusitis without polyps.

Martin J Burton1, Matthew W Ryan, Richard M Rosenfeld

  • 1Department of Otolaryngology, University of Oxford and the Radcliffe Infirmary, Oxford, UK.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|January 18, 2014
PubMed
Summary
This summary is machine-generated.

Topical steroids show therapeutic benefits for chronic rhinosinusitis without nasal polyps. This Cochrane Review found no increased adverse events compared to placebo, supporting their use in otolaryngology.

Keywords:
chronic rhinosinusitissystematic reviewtopical corticosteroid therapy

More Related Videos

Intranasal Administration of CNS Therapeutics to Awake Mice
07:15

Intranasal Administration of CNS Therapeutics to Awake Mice

Published on: April 8, 2013

60.0K
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.4K

Related Experiment Videos

Last Updated: May 3, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.8K
Intranasal Administration of CNS Therapeutics to Awake Mice
07:15

Intranasal Administration of CNS Therapeutics to Awake Mice

Published on: April 8, 2013

60.0K
Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
03:40

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

1.4K

Area of Science:

  • Otolaryngology-Head and Neck Surgery
  • Evidence-Based Medicine

Background:

  • Chronic rhinosinusitis without polyps is a common condition.
  • Treatment options aim to reduce inflammation and improve symptoms.

Purpose of the Study:

  • To evaluate the efficacy and safety of topical steroids for chronic rhinosinusitis without polyps.
  • To provide clinicians with evidence to guide treatment decisions.

Main Methods:

  • Systematic review of randomized controlled trials.
  • Comparison of topical steroids versus placebo.

Main Results:

  • Good evidence supports the therapeutic benefits of topical steroids.
  • No significant increase in adverse events was observed compared to placebo.

Conclusions:

  • Topical steroids are an effective and safe treatment option for chronic rhinosinusitis without polyps.
  • Findings support the use of topical steroids in clinical practice for this condition.