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Published on: August 22, 2025
[Meta-analysis on the risk factors for stomal recurrence after total laryngectomy]
Xiaoli Sheng1, Siyi Zhang1, Xinhan Song1
1Department of Otolaryngology, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou, 510080, China.
Objective:
To evaluate the risk factors of stomal recurrence in patients after total laryngectomy.
Method:
A thorough literature search was performed among Wanfang database, Chinese Scientific Journals Database of VIP and pubmed database. Meta analysis was performed on a total of 2725 patients in 2 Chinese papers and 6 English papers which met the inclusion criteria. Data was analyzed by RevMan 5.0 software.
Result:
Subglottic and transglottic location (tumor location), the extent of the tumor of the primary site (T4), preoperative tracheotomy were important risk factors of recurrence after total laryngectomy.
Conclusion:
Subglottic and transglottic location (tumor location), the extent of the tumor of the primary site (T4), preoperative tracheotomy were related to stomal recurrence after total laryngectomy.
