Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systematic review of diffusion tensor imaging in spina bifida myelomeningocele: clinical implications in the era of prenatal repair.

Journal of neurosurgery. Pediatrics·2026
Same author

Challenges and prospects of 2D electronics for future monolithic complementary field-effect transistors.

Nature communications·2026
Same author

Hybrid Interfaces of 2D Materials with Polymers for Emerging Electronics and Energy Devices.

Materials (Basel, Switzerland)·2026
Same author

Neuroticism heterogeneity through item-level associations in resting-state functional connectivity.

Communications biology·2025
Same author

A Woman With Right Upper Quadrant Pain.

Annals of emergency medicine·2025
Same author

The burden of brooding on neural error processing: The role of repetitive negative thinking in major depressive disorder with and without comorbid anxiety disorders.

Journal of affective disorders·2024
Same journal

Targeting neurodevelopmental miR132-3p promotes neuroprotection and axon regeneration after optic nerve injury in mice.

Brain research·2026
Same journal

Variability in acoustic startle response and prepulse inhibition across adulthood in Fragile X messenger ribonucleoprotein 1 knockout mice.

Brain research·2026
Same journal

Transcriptome-guided modeling reveals insulin-related metabolic dysfunction in SCA3 mouse cerebellum.

Brain research·2026
Same journal

Intranasal stromal cell-derived factor-1α mitigates parkinsonian deficits via dual modulation of neuroinflammation and gut microbiota in MPTP-induced models.

Brain research·2026
Same journal

Emotions, the amygdala, and the right hemisphere.

Brain research·2026
Same journal

Electroacupuncture treatment enhances hippocampal growth hormone level and restores mitochondrial function in vascular dementia rats.

Brain research·2026
See all related articles

Related Experiment Video

Updated: May 3, 2026

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
09:16

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

3.7K

Source recognition by stimulus content in the MTL.

Heekyeong Park1, Cheryl Abellanoza1, James Schaeffer1

  • 1Department of Psychology, University of Texas at Arlington, College of Science, 501S. Nedderman Drive, Arlington, TX 76019, United States.

Brain Research
|February 4, 2014
PubMed
Summary
This summary is machine-generated.

Source memory, crucial for episodic memory, relies on the medial temporal lobe (MTL). This fMRI study reveals distinct neural patterns in the MTL for word versus picture source recognition and novelty detection.

Keywords:
HippocampusMTLSource memoryStimulus contentfMRI

More Related Videos

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

44.4K
Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography
09:25

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

7.4K

Related Experiment Videos

Last Updated: May 3, 2026

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
09:16

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

3.7K
Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

44.4K
Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography
09:25

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

7.4K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neuroimaging

Background:

  • Source memory is vital for distinguishing similar events within episodic memory.
  • The medial temporal lobe (MTL) plays a critical role in memory functions.
  • Understanding how stimulus content influences neural correlates of source memory is essential.

Purpose of the Study:

  • To investigate content-specific neural differences in medial temporal lobe (MTL) activity during source memory retrieval.
  • To examine how the brain processes novel information across different stimulus types (words vs. pictures).
  • To elucidate the role of the hippocampus and surrounding MTL cortices in source recognition and novelty detection.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was used to measure brain activity.
  • Participants integrated verbal or pictorial items with contextual information (color).
  • Source recognition and novelty detection were assessed for both words and pictures.

Main Results:

  • Source recognition, regardless of content, activated the left anterior hippocampus and right posterior hippocampus.
  • Word-specific source recognition involved the left perirhinal cortex; picture-specific recognition involved the left posterior hippocampus.
  • Novelty detection common to both stimuli engaged the left anterior and right posterior hippocampus, with content-specific activations in MTL regions.

Conclusions:

  • The hippocampus is integral to source recognition and novelty detection across various stimulus contents.
  • MTL cortices act as an interface for processing new information, highlighting their role in memory formation.
  • These findings underscore the significance of the MTL in encoding and retrieving both familiar and novel experiences.