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(33)S as a cooperative capturer for BNCT
J Praena1, M Sabaté-Gilarte1, I Porras2
1Universidad de Sevilla, Spain; Centro Nacional de Aceleradores (US-JA-CSIC), Seville, Spain.
The presence of Sulfur-33 (33S) may enhance radiation dose in Boron Neutron Capture Therapy (BNCT) using 13.5keV neutrons. Further experiments are needed to confirm these findings due to limited cross-section data.
Area of Science:
- Nuclear physics
- Medical physics
- Radiotherapy
Background:
- Sulfur-33 (33S) is a stable sulfur isotope.
- Neutron-induced reactions with 33S predominantly release alpha particles.
- Accurate cross-section data for 33S is scarce, especially below 10keV.
Purpose of the Study:
- To investigate the potential enhancement of absorbed and biologically weighted dose in Boron Neutron Capture Therapy (BNCT).
- To evaluate the impact of 33S presence in BNCT treatments utilizing 13.5keV neutrons.
- To address the need for experimental validation of 33S neutron cross-section data.
Main Methods:
- Monte Carlo simulations were employed to model dose enhancement.
- Kerma-fluence factors for ICRU-4 tissue were calculated using standard weighting factors.
- A new experimental setup was designed and tested at the n_TOF facility at CERN.
Main Results:
- Simulations indicated a potential enhancement in absorbed and biologically weighted dose due to 33S.
- The study highlighted the critical dependence on scarce 33S(n,α)30Si cross-section data.
- Previous research established a high resonance at 13.5keV, but with discrepant parameters.
Conclusions:
- The presence of 33S may significantly influence dose deposition in BNCT.
- Experimental validation of 33S neutron cross-section data is crucial.
- An experiment at CERN's n_TOF facility is scheduled to gather necessary data.
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