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Updated: May 3, 2026

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Published on: February 23, 2011
Inherited thrombophilias and adverse pregnancy outcomes: a review of screening patterns and recommendations
William B Davenport1, William H Kutteh2
1Department of Obstetrics and Gynecology, University of Vermont, 89 Beaumont Avenue, Given C262, Burlington, VT 05406, USA.
Abstract:
Historically, much controversy has existed regarding the association of inherited thrombophilias with adverse pregnancy outcomes. The current guidelines do not recommend screening unless a personal history of venous thromboembolism is present, but the authors' survey of physician screening patterns has suggested that up to 40% of physicians may screen contrary to the current guidelines. This article summarizes the existing evidence for each inherited thrombophilia and reviews the current guidelines.
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