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Oncogenic mechanisms in Burkitt lymphoma

Roland Schmitz1, Michele Ceribelli, Stefania Pittaluga

  • 1Lymphoid Malignancies Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892.

Cold Spring Harbor Perspectives in Medicine
|February 5, 2014
PubMed
Summary

Transcription factor TCF-3 drives Burkitt lymphoma by activating oncogenes and promoting cell growth. Targeting TCF-3 offers new therapeutic strategies for this aggressive B-cell cancer.

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