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A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
A comparison between the AASM 2012 and 2007 definitions for detecting hypopnea.
Ahmed S BaHammam1, Amr Obeidat, Kashmira Barataman
1University Sleep Disorders Center and National Plan for Science and Technology, College of Medicine, King Saud University, Box 225503, Riyadh, 11324, Saudi Arabia, ashammam2@gmail.com.
The 2012 American Academy of Sleep Medicine (AASM) hypopnea definition detects significantly more events than older criteria, impacting obstructive sleep apnea (OSA) diagnosis. The 2007 "Recommended" definition resulted in lower apnea-hypopnea indices (AHIs) compared to other criteria.
Area of Science:
- Sleep Medicine
- Respiratory Physiology
Background:
- Obstructive sleep apnea (OSA) diagnosis relies on accurate event detection during polysomnography (PSG).
- The American Academy of Sleep Medicine (AASM) has revised hypopnea definitions, potentially altering diagnostic outcomes.
- Comparing these definitions is crucial for consistent OSA diagnosis and management.
Purpose of the Study:
- To compare apnea-hypopnea indices (AHIs) using three AASM hypopnea definitions.
- To evaluate the impact of AASM definition modifications on AHI and OSA diagnosis.
Main Methods:
- 100 patients undergoing diagnostic PSG for OSA were analyzed.
- Hypopneas were scored using 2007 AASM "Alternative" (H Alt), 2007 AASM "Recommended" (H Rec), and 2012 AASM (H 2012) criteria.
- Bland-Altman plots assessed agreement between scoring methods.
Main Results:
- The 2012 AASM criteria yielded a significantly higher mean AHI (37.9/h) compared to H Rec (14.8/h) and H Alt (29.6/h).
- Bland-Altman analysis indicated that the H 2012 definition consistently detected more hypopnea events.
- Significant differences in AHI were observed across all three scoring definitions (p<0.05).
Conclusions:
- A significant difference exists in hypopnea event detection among the H 2012, H Rec, and H Alt definitions.
- The 2007 AASM "Recommended" definition tends to underestimate AHI compared to the other two.
- Updated AASM hypopnea criteria influence OSA diagnostic rates.
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