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Updated: May 3, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
An interdisciplinary approach to personalized medicine: case studies from a cardiogenetics clinic
Kathleen E Erskine1, Eleanor Griffith2, Nicole Degroat3
1Department of Obstetrics & Gynecology & Women's Health, Division of Reproductive Genetics, Albert Einstein College of Medicine/Montefiore Medical Center, 1695 Eastchester Road, Suite 301, Bronx, NY, USA.
Insights
An interdisciplinary model of care is essential for managing inherited conditions like long QT syndrome. This approach offers personalized, comprehensive support for families facing complex genetic cardiac issues.
Area of Science:
- Genetics
- Cardiology
- Personalized Medicine
Background:
- Inherited cardiac arrhythmias, such as long QT syndrome, present complex challenges.
- Effective management requires expertise across multiple medical, psychological, and ethical domains.
Purpose of the Study:
- To highlight the benefits of an interdisciplinary care model for inherited cardiac conditions.
- To showcase the Montefiore-Einstein Center for CardioGenetics' approach to personalized patient care.
Main Methods:
- Presentation of four patient care vignettes.
- Illustrating the integration of genetic, psychological, ethical, and medical expertise.
- Demonstrating the collaborative nature of interdisciplinary clinics.
Main Results:
- Interdisciplinary clinics facilitate collaboration among diverse specialists.
- This model enables individualized and comprehensive care for complex inherited conditions.
- Patient care vignettes exemplify the model's capacity to address multifaceted issues.
Conclusions:
- An interdisciplinary approach is crucial for addressing the complexities of genetic cardiac conditions.
- Personalized medicine is enhanced through collaborative, multi-specialty care models.
- The advantages of interdisciplinary clinics will become increasingly apparent as genetic discoveries advance.
Abstract:
In the genomic age, the challenges presented by various inherited conditions present a compelling argument for an interdisciplinary model of care. Cardiac arrhythmias with a genetic basis, such as long QT syndrome, require clinicians with expertise in many specialties to address the complex genetic, psychological, ethical and medical issues involved in treatment. The Montefiore-Einstein Center for CardioGenetics has been established to provide personalized, interdisciplinary care for families with a history of sudden cardiac death or an acute cardiac event. Four vignettes of patient care are presented to illustrate the unique capacity of an interdisciplinary model to address genetic, psychological, ethical and medical issues. Because interdisciplinary clinics facilitate collaboration among multiple specialties, they allow for individualized, comprehensive care to be delivered to families who experience complex inherited medical conditions. As the genetic basis of many complex conditions is discovered, the advantages of an interdisciplinary approach for delivering personalized medicine will become more evident.
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