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Updated: May 3, 2026

Design of a Biocompatible Drug-Eluting Tracheal Stent in Mice with Laryngotracheal Stenosis
Published on: January 21, 2020
Stent hypersensitivity and infection in sinus cavities
Nicholas G Kounis1, George D Soufras1, George Hahalis1
1of Department of Medical Sciences, Patras Highest Institute of Education and Technology, Patras, Achaia, Greece.
Retained steroid-eluting sinus stents can cause inflammation, hypersensitivity, and infection. Their removal is crucial for resolving chronic rhinosinusitis symptoms.
Area of Science:
- Otolaryngology
- Allergy and Immunology
- Infectious Diseases
Background:
- Refractory chronic rhinosinusitis often requires surgical intervention.
- Drug-eluting stents are used in endoscopic sinus surgery to manage inflammation.
- Complications from retained surgical materials are rarely reported.
Purpose of the Study:
- To report a novel case of complications arising from retained steroid-eluting catheters after endoscopic sinus surgery.
- To highlight the potential for hypersensitivity and infection associated with retained sinus stents.
- To review existing literature on stent-related issues in sinus surgery.
Main Methods:
- A case report of a 45-year-old male patient with recalcitrant chronic rhinosinusitis.
- Functional endoscopic sinus surgery was performed, revealing retained steroid-eluting catheters.
- Microbiological cultures were obtained from the retrieved stents.
Main Results:
- Retained catheters caused persistent mucosal inflammation, granulation tissue, and hypersensitivity.
- Infection with Stenotrophomonas maltophilia, Klebsiella oxytoca, Staphylococcus, and Streptococcus anginosus was identified.
- Successful surgical removal of the stents resolved symptoms without recurrence.
Conclusions:
- Retained drug-eluting stents can lead to significant complications including inflammation, hypersensitivity, and bacterial infection.
- Prompt identification and removal of retained sinus stents are essential for patient recovery.
- This case underscores the importance of meticulous surgical technique and material awareness in endoscopic sinus surgery.
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