The necessity of bone densitometry for patients taking selective serotonin reuptake inhibitors
Ki-Yong An1, Woo-Jin Shin1, Kyu-Jung Lee1
1Department of Orthopedic Surgery, Gwangju Veterans Hospital, Gwangju, Korea.
Background:
To analyze the necessity of bone densitometry for patients long-term taking selective serotonin reuptake inhibitors (SSRI) over a long period of time, which is one of the risk factors of osteoporosis.
Methods:
We selected patients from 5 veterans hospitals who took SSRI for more than 2 months while taking bone densitometry on a regular basis.
Results:
Of the 85 patients from a total of 5 veterans hospitals taking SSRI for more than two months, only 34 patients were under diagnosis and treatment measures of osteoporosis through checking each person's bone mineral density.
Conclusions:
It is necessary for patients taking SSRI to check bone density on a regular basis.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Dose-Response Relationship: Selectivity and Specificity
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
Antidepressant Drugs: MAOIs and Other Agents
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists
Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance
A study on guinea pigs examined the...


