Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

7.0K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.0K
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

30
Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
30
Goiter01:27

Goiter

32
Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...
32
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

28
Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH...
28

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Predisposition for Type 2 Diabetes Mellitus and Metabolic Syndrome.

Balkan journal of medical genetics : BJMG·2023
Same author

Unconventional Spin Relaxation Involving Localized Vibrational Modes in Ho Single-Atom Magnets.

Physical review letters·2020
Same author

EMERGENCY SURGICAL TRACHEAL DECOMPRESSION IN A HUGE RETROSTERNAL GOITER.

Acta endocrinologica (Bucharest, Romania : 2005)·2019
Same author

NEUROENDOCRINE TUMORS OF THE LUNG WITH SURGICAL RESECTION AND LYMPH NODE DISSECTION IN A TERTIARY THORACIC SURGERY CENTER.

Acta endocrinologica (Bucharest, Romania : 2005)·2019
Same author

Post-treatment periapical periodontitis X-ray versus CBCT - a case report.

Journal of medicine and life·2016
Same author

Practical use of the Virtual Cell Based Assay: Simulation of repeated exposure experiments in liver cell lines.

Toxicology in vitro : an international journal published in association with BIBRA·2016

Related Experiment Video

Updated: May 3, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

1.3K

Cervico-mediastinal thyroid masses - our experience.

C Nistor, A Ciuche, C Motaş

    Chirurgia (Bucharest, Romania : 1990)
    |February 15, 2014
    PubMed
    Summary

    Surgical excision is the only treatment for cervico-mediastinal thyroid masses. This study found that cervical incision and bipolar approaches achieve safe resection with excellent outcomes and no mortality.

    More Related Videos

    "Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach
    07:45

    "Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

    Published on: November 28, 2025

    284
    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
    03:55

    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

    Published on: June 9, 2023

    1.2K

    Related Experiment Videos

    Last Updated: May 3, 2026

    Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
    04:09

    Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

    Published on: September 20, 2024

    1.3K
    "Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach
    07:45

    "Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

    Published on: November 28, 2025

    284
    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
    03:55

    Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

    Published on: June 9, 2023

    1.2K

    Area of Science:

    • Thoracic Surgery
    • Endocrinology
    • Surgical Oncology

    Background:

    • Cervico-mediastinal goiters and thyroid masses have diverse definitions and classifications.
    • A 22-year retrospective analysis of clinical presentation, diagnostics, and surgical outcomes for these masses was conducted.

    Purpose of the Study:

    • To analyze clinical presentation, diagnostic procedures, and surgical techniques for cervico-mediastinal thyroid masses.
    • To evaluate post-operative complications and results in relation to surgical approaches.

    Main Methods:

    • A review of 130 patients (77 female, 53 male; mean age 53) who underwent surgery for retrosternal thyroid masses between 1991 and 2012.
    • Cervico-thoracic CT scans were used for diagnosis and assessment of intrathoracic progression and tracheal compression.
    • Surgical approaches included cervical incision (106 cases), cervicotomy with partial upper sternotomy (20 cases), full sternotomy (3 cases), and axillary thoracotomy (1 case).

    Main Results:

    • All 130 patients achieved successful removal of the thyroid mass and tracheal decompression.
    • Post-operative outcomes were highly satisfactory, with no respiratory distress and normal vocal cord function.
    • No post-operative mortality was recorded.

    Conclusions:

    • Surgical excision is the definitive treatment for cervico-mediastinal thyroid masses, regardless of respiratory distress.
    • Cervical incision is effective for excising these masses, and bipolar approaches offer excellent outcomes for large, complex cases.
    • The study highlights the importance of tailored surgical techniques for safe and successful resection.