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Related Concept Videos

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Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
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Related Experiment Video

Updated: May 2, 2026

Author Spotlight: Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model
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[Hiccup, a diagnostic challenge].

Sonia Pankl1, Mariano A Quezel, Julio E Bruetman

  • 1Servicio de Clínica Médica, Hospital Británico de Buenos Aires, Argentina.

Medicina
|February 25, 2014
PubMed
Summary
This summary is machine-generated.

Rebellious hiccups, a persistent condition, were resolved in a 75-year-old male by resecting an ethmoid sinus tumor. This case highlights a rare cause of intractable hiccups and its successful treatment.

Keywords:
hiccupreflex arc

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Area of Science:

  • Neurology
  • Otolaryngology
  • Oncology

Background:

  • Hiccups are involuntary diaphragmatic contractions causing a distinct sound.
  • Classified by duration: attack, persistent, or intractable (rebellious).
  • Rebellious hiccups significantly impair quality of life, disrupting sleep and causing distress.

Observation:

  • A 75-year-old male presented with a 3-year history of rebellious hiccups and belching.
  • Symptoms were refractory to chlorpromazine, a common treatment.
  • The patient experienced severe sleep disruption due to the persistent hiccups.

Findings:

  • Extensive evaluation revealed a right ethmoid sinus tumor as the underlying cause.
  • Surgical resection of the tumor was performed.
  • Following tumor resection and radiotherapy, the patient's hiccups completely resolved.

Implications:

  • Ethmoid sinus tumors represent a rare but significant etiology for rebellious hiccups.
  • This case underscores the importance of thorough diagnostic evaluation for refractory symptoms.
  • Successful treatment involved a multidisciplinary approach, combining surgery and radiotherapy.