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Infantile fibrosarcoma in a child: a case report
A Hashemi1, S Tefagh2, A Seifadini3
1Department of Pediatrics, Hematology, Oncology and Genetic Research Center, Shahid Sadoughi University of Medical Sciences Health Services, Yazd, Iran.
Insights
Infantile fibrosarcoma, a rare soft tissue tumor, can recur but has a good prognosis in children. Successful treatment involves surgery and chemotherapy, with metastasis being uncommon.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
Background:
- Infantile fibrosarcoma is a rare pediatric soft tissue tumor, primarily affecting extremities.
- While histopathologically similar to adult forms, infantile fibrosarcoma exhibits a significantly better survival prognosis.
- Recurrence is common, but metastasis rates are low, especially in younger children.
Observation:
- A case report details a nine-year-old girl with a recurrent left hand mass.
- Pathological examination revealed sheets of spindle-shaped cells, indicative of infantile fibrosarcoma.
- The patient presented with a relapsing mass, necessitating intervention.
Findings:
- The diagnosis of infantile fibrosarcoma was confirmed through pathological findings.
- The patient received a combination of surgical intervention and chemotherapy.
- The treatment resulted in a successful outcome with tumor regression.
Implications:
- Infantile fibrosarcoma should be considered in the differential diagnosis of pediatric soft tissue masses.
- The condition generally has a favorable prognosis with uncommon distant metastasis.
- Surgery is the primary treatment, with chemotherapy and radiotherapy aiding in metastasis reduction.
Background:
Infantile Fibrosarcoma is a rare soft tissue tumor in infants and children mostly located in extremities. An infantile and adult form has similar histopathological patterns but survival prognosis is much better in infantile form. Recurrence of infantile fibrosarcoma is common but the rates of metastasis are less than 10 percent in children younger than five Years and 50 percent in children more than 10 years old.
Case Presentation:
In this case report, we presented a nine years girl with a relapsing mass in her left hand. The pathologic findings showed sheets of spindle-shaped cells with suggested diagnose of infantile fibrosarcoma. She was successfully treated with combination of surgery and chemotherapy with a good outcome.
Conclusion:
Infantile fibrosarcoma is a differential diagnose of soft tissue mass in infants and children. It has a good prognosis and distant metastasis is uncommon. Choice of treatment is surgery but chemotherapy and radiotherapy were useful in decrease metastasis.
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