Related Experiment Video
Updated: May 2, 2026

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging
Published on: March 13, 2019
Unidirectional light-driven molecular motors based on overcrowded alkenes.
Arjen Cnossen1, Wesley R Browne, Ben L Feringa
1Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Researchers review progress in light-driven molecular motors based on overcrowded alkenes. Both first and second-generation motors are discussed, highlighting their potential for nanoscale work and applications.
Area of Science:
- Nanotechnology
- Molecular Engineering
- Supramolecular Chemistry
Background:
- Nanotechnology has advanced significantly over the past two decades, creating nanoscale versions of macroscopic devices.
- Molecular nanotechnology focuses on creating functional molecular machines, with rotaxane-based linear motors and overcrowded alkene-based rotary motors showing particular promise.
- Overcrowded alkenes are a key structural motif for developing rotary molecular motors capable of performing work at the nanoscale.
Purpose of the Study:
- To review the progress in the field of light-driven molecular motors based on overcrowded alkenes.
- To discuss the development and characteristics of both first and second-generation molecular motors.
- To explore the potential applications of these molecular motors in various fields.
Main Methods:
- Review of existing literature on light-driven molecular motors.
- Analysis of the design principles and synthesis strategies for overcrowded alkene-based motors.
- Discussion of experimental data and theoretical studies related to motor function and efficiency.
Main Results:
- Significant advancements have been made in the design and synthesis of light-driven molecular motors.
- First-generation motors demonstrated proof-of-concept, while second-generation motors exhibit improved efficiency and control.
- Overcrowded alkene structures provide a versatile platform for achieving controlled unidirectional rotation.
Conclusions:
- Light-driven molecular motors based on overcrowded alkenes represent a significant achievement in molecular nanotechnology.
- These motors hold great potential for applications in areas such as targeted drug delivery, nanoscale robotics, and advanced materials.
- Continued research is expected to yield more sophisticated and efficient molecular motors with diverse functionalities.
Related Concept Videos
Radical Anti-Markovnikov Addition to Alkenes: Mechanism
The mechanism starts with chain initiation, which involves two steps. In the first chain initiation step, a weak peroxide bond is homolytically cleaved upon mild heating to form two alkoxy radicals. In the second initiation step, a hydrogen atom is abstracted by the alkoxy...
Hydroboration-Oxidation of Alkenes
Microtubule Associated Motor Proteins
Free-Radical Chain Reaction and Polymerization of Alkenes
Reduction of Alkenes: Catalytic Hydrogenation
Metals like palladium, platinum, and nickel are commonly used in their solid forms — fine powder on an inert surface. As these catalysts remain insoluble in the reaction mixture, they are referred to as heterogeneous catalysts.
The hydrogenation process takes place on the...
Acid-Catalyzed Hydration of Alkenes

