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Updated: Dec 16, 2025
Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
Published on: March 3, 2020
Light-induced molecular rotation triggers on-demand release from liposomes
Laís Ribovski1, Qihui Zhou, Jiawen Chen
1University of Groningen, University Medical Center Groningen, Department of Biomedical Engineering, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands. p.van.rijn@umcg.nl i.zuhorn@umcg.nl.
Abstract:
Controllable molecular release from delivery vehicles is essential to successfully reduce drug toxicity and improve therapeutic efficacy. Light-powered hydrophobic molecular motors were therefore incorporated in liposomes to use molecular rotation to facilitate on-demand release. The extent of the release was precisely controlled by irradiation times, providing a simple yet sophisticated responsive molecular nanocarrier.
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