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Possible proarrhythmic effects of tocainide in dilated cardiomyopathy
S L Brownstein1, L Constantin, M G Kienzle
1Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City.
Pacing and Clinical Electrophysiology : PACE
|July 1, 1988
Abstract:
A patient with a dilated cardiomyopathy experienced a cardiac arrest when taking tocainide for asymptomatic nonsustained ventricular tachycardia. After successful resuscitation from ventricular fibrillation and exclusion of a myocardial infarction, an electrophysiological evaluation was performed. Drug-free study #1 revealed no induction of ventricular tachycardia. A tocainide study revealed induction of sustained monomorphic ventricular tachycardia. Drug-free study #2 revealed induction of nonsustained ventricular tachycardia. This report illustrates a possible proarrhythmic effect of tocainide.