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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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An imaging approach to diffuse white matter changes.

Nilesh K Desai1, Mark E Mullins2

  • 1Division of Neuroradiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Road Northeast, EUH B115, Atlanta, GA 30322, USA; Children's Healthcare of Atlanta at Egleston and Town Center, Atlanta, GA 30329, USA.

Radiologic Clinics of North America
|March 4, 2014
PubMed
Summary
This summary is machine-generated.

White matter disorders encompass a wide range of conditions, from congenital metabolic issues to acquired diseases like chronic ischemic microvascular white matter disease. Magnetic resonance imaging (MRI) has significantly advanced the diagnostic capabilities for these neurological conditions.

Keywords:
DiffuseLeukodystrophyLeukoencephalopathyMRIT2White matter

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Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • White matter disorders are a diverse group of neurological conditions.
  • These disorders range from congenital metabolic diseases to acquired conditions like chronic ischemic microvascular white matter disease.
  • Accurate diagnosis is crucial for effective management and treatment.

Purpose of the Study:

  • To highlight the significant impact of magnetic resonance imaging (MRI) on the diagnostic evaluation of white matter disorders.
  • To underscore the heterogeneity of white matter disorders, spanning congenital and acquired etiologies.

Main Methods:

  • Review of diagnostic advancements in white matter disorders.
  • Emphasis on the role of magnetic resonance imaging (MRI) in clinical practice.
  • Discussion of the spectrum of white matter diseases evaluated.

Main Results:

  • Magnetic resonance imaging (MRI) has transformed the diagnostic process for white matter disorders.
  • MRI enables detailed visualization and characterization of white matter abnormalities.
  • The diagnostic utility of MRI spans the entire spectrum of these heterogeneous conditions.

Conclusions:

  • Magnetic resonance imaging (MRI) is an indispensable tool in diagnosing white matter disorders.
  • The continued evolution of MRI techniques promises further improvements in diagnostic accuracy.
  • Understanding the heterogeneity of white matter disorders is key to leveraging MRI effectively.