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Updated: May 2, 2026

Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies
Published on: August 25, 2023
Left ventricular geometry and systolic function improvement after percutaneous closure of aortic prosthetic
Eftychia Demerouti1, Evangelos Leontiadis2, George Karatasakis3
1Noninvasive Diagnostics Department, Cardiology Section, Onassis Cardiac Surgery Center, Athens, Greece. efidemeri@otenet.gr
Abstract:
Paravalvular leak (PVL) represents a potential complication of valve replacement surgery. The 'gold standard' treatment for patients with severe prosthetic dysfunction, hemolysis or symptoms, is surgery. Reoperative valve surgery for such patients is related to high morbidity and mortality rate. The percutaneous closure of PVL is feasible and safe, when performed at experienced interventional cardiologic centers. Herein, the case is reported of a patient who showed a significant improvement in left ventricular systolic function after transcatheter closure of an aortic prosthetic PVL with an Amplatzer duct occluder II (ADO II). A review of the current literature is also provided.

