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Hemoglobin cut-off values in healthy Turkish infants

Ahmet Arvas1, Emel Gür, Durmuş Doğan

  • 1Department of Pediatrics, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey, aarvas@istanbul.edu.tr.

World Journal of Pediatrics : WJP
|March 7, 2014
PubMed

Insights

This study determined hemoglobin cut-off values for infant anemia, finding lower levels than WHO criteria in a developing country. Re-evaluating these values is crucial for infant health and development.

Area of Science:

  • Pediatrics
  • Hematology
  • Public Health

Background:

  • Anemia poses a significant public health risk, increasing morbidity and mortality.
  • Establishing accurate diagnostic criteria for infant anemia is essential.

Purpose of the Study:

  • To determine the specific hemoglobin (Hb) cut-off values for diagnosing anemia in healthy infants.
  • To compare these values with existing World Health Organization (WHO) criteria.

Main Methods:

  • A retrospective cross-sectional study involving 1484 healthy infants aged 4-24 months.
  • Analysis of hemoglobin levels across four age groups.
  • Evaluation of Hb levels in relation to maternal age, birth weight, weight gain rate, feeding practices, and gender.

Main Results:

  • Hemoglobin cut-off values (5th percentile) were established for different infant age groups (e.g., 97 g/L at 4 months, 93 g/L at 6 months).
  • Determined cut-off values were generally lower than WHO criteria, potentially due to iron status variations in the studied population.
  • Female infants showed higher Hb levels, with a significant difference noted at 6 months; no significant associations were found with maternal age, birth weight, or weight gain rate.

Conclusions:

  • Current hemoglobin cut-off values for infant anemia may require re-evaluation.
  • Recommended cut-offs should align with the specific growth and developmental context of the community.
  • Further research is needed to establish precise normal Hb levels for infants in developing countries.
Abstract

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