Related Experiment Video
Updated: May 7, 2026
Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
The effect of multi-sensory stimuli used during vaccination on pain and physiological parameters in infants: A
Kadriye Şahin1, Suzan Yıldız2, Emel Gür3
1Harran University, Health Science Faculty, Department of Pediatric Nursing, Turkey; Şanlıurfa-Mardin, Highway 18.Km Sanliurfa, Turkey.
Purpose:
The study examine the effect of Multi-Sensory Stimulus Method (MSSM) during vaccination in infants on pain and physiological parameters.
Methods:
The study was a randomized controlled trial between March and December 2023. A total of 96 infants aged 2-6 months were included, divided into 3 intervention and 1 control group. The MSSM was applied to the first intervention group by the nurse, and to the second intervention group by the mother. Third group infants were only breastfed without MSSM, while the control group (CG) received standard care. Data were collected via forms, pain scale, and physiological parameters. Pain, peak heart rate (HRP), and oxygen saturation (SpO₂) were evaluated at 5 points: 5 min before, 2 min before, immediately before and after vaccination, 2 min after, and 5 min after the vaccination. Process was video-recorded. Data analyzed with descriptive stats, ANOVA, Chi-Square, Bonferroni tests (p < 0.05).
Results:
No significant differences among groups in terms of descriptive characteristics (p > 0.05). Significant differences found in total FLACC scores and SpO₂ values measured throughout the procedure, while no statistically significant difference was observed in HRP values (p < 0.05). MSSM by mother/nurse had lower FLACC scores than breastfeeding and control groups. Crying duration in the CG was longer than MSSM groups was applied by the mother or nurse.
Conclusion:
MSSM applied by mothers and nurses during vaccination reduced pain, helped maintain SpO₂, and no effect on HRP.
Implications To Practice:
MSSM supports atraumatic and family-centered care practices, its use is recommended during painful procedures.
Clinical Trials Number:
NCT06291519.
More Related Videos
09:38Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
Published on: January 29, 2014
06:29Electrophysiological Measurement of Noxious-evoked Brain Activity in Neonates Using a Flat-tip Probe Coupled to Electroencephalography
Published on: November 29, 2017
