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Related Concept Videos

Skin Cancer01:30

Skin Cancer

5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Abnormal Proliferation02:23

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Abnormal Proliferation02:23

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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Updated: May 2, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Giant Basal cell carcinoma.

Shayna S C Rivard, Michael L Crandall, Neil F Gibbs

    Journal of Special Operations Medicine : a Peer Reviewed Journal for SOF Medical Professionals
    |March 8, 2014
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    Summary
    This summary is machine-generated.

    Servicemembers face risks of skin cancer due to sun exposure. This case highlights giant basal cell carcinoma (GBCC), a rare but potentially fatal skin cancer, emphasizing the need for prevention in the military population.

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    Area of Science:

    • Dermatology
    • Oncology
    • Military Medicine

    Background:

    • Military personnel experience significant sun exposure, increasing skin cancer risk.
    • Basal cell carcinoma (BCC) is the most prevalent form of skin cancer.
    • Giant basal cell carcinoma (GBCC) is a rare subtype of BCC.

    Observation:

    • A 36-year-old active duty Seabee presented with a large (6 cm) plaque on his left shoulder.
    • The lesion evolved from an erythematous papule over 10 years.

    Findings:

    • The patient was diagnosed with giant basal cell carcinoma (GBCC).
    • Giant basal cell carcinoma (GBCC) accounts for only 0.5% to 1% of all BCC cases.
    • GBCC carries a risk of metastasis and mortality.

    Implications:

    • This case underscores the importance of recognizing and managing rare BCC variants.
    • Preventive strategies and early diagnosis are crucial for military populations.
    • Understanding GBCC is vital for potentially fatal skin cancer outcomes.