Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Electrical ablation with a balloon electrode array: chronic electrophysiologic response.

L Harris1, L L Mickleborough, N Shaikh

  • 1Department of Medicine and Surgery, Women's College Hospital, University of Toronto, Ontario, Canada.

Pacing and Clinical Electrophysiology : PACE
|September 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Replication origin firing capacity indicates ATR inhibitor sensitivity.

Nature communications·2026
Same author

Successful treatment of pulmonary melioidosis in an Australian dog.

Australian veterinary journal·2026
Same author

Review of the first 5 years of dedicated FDG PET/CT for Cardiac Inflammation.

Irish medical journal·2025
Same author

PRECISION MEDICINE AND ANAESTHESIA: CURRENT CLINICAL AND GENOMICS APPROACHES.

Georgian medical news·2025
Same author

Environmental considerations for the decommissioning of subsea cables.

Journal of environmental management·2025
Same author

Stroke incidence, mortality and disability-adjusted life years (DALYs) trends in association with air pollution, dietary and metabolic risk factors in Gulf Cooperation Council countries: Global burden of disease data based analysis 1990-2021.

Saudi medical journal·2025
Same journal

A Case of Permanent Pacemaker Implantation via the Epicardial Approach Using the 3830 Lead in an 11-Day-Old Neonate (With Follow-Up of the Above Case).

Pacing and clinical electrophysiology : PACE·2026
Same journal

Cryoballoon Versus Radiofrequency Ablation for Persistent Atrial Fibrillation: Meta-Analysis of Randomized Trials.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Tilt Test Duration in Suspected Vasovagal Syncope: Temporal Patterns and Diagnostic Yield in Patients From Central China.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Combined Leadless Pacing and Subcutaneous ICD Therapy in Long QT Syndromes.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Association of Anesthesia Modality With Procedural Parameters and Clinical Outcomes in PVI for Atrial Fibrillation.

Pacing and clinical electrophysiology : PACE·2026
Same journal

Zero-Fluoroscopy Cryoballoon Ablation for Paroxysmal Atrial Fibrillation in a Patient With Dextrocardia: A Case Report.

Pacing and clinical electrophysiology : PACE·2026
See all related articles

This study explored electrical ablation for ventricular arrhythmias. The procedure created an inert scar, effectively preventing induced arrhythmias in dogs long-term.

Area of Science:

  • Cardiovascular Electrophysiology
  • Medical Device Technology
  • Surgical Innovation

Background:

  • Intraoperative endocardial electrode arrays enable multi-site ventricular recordings.
  • This facilitates exploration of electrical ablation as an alternative to ventriculotomy.
  • Current ablative techniques often require invasive surgical procedures.

Purpose of the Study:

  • To evaluate the long-term electrophysiologic and structural effects of an adapted intraoperative electrical ablation procedure on ventricular myocardium.
  • To determine the efficacy of this technique in preventing induced ventricular arrhythmias.

Main Methods:

  • Seven dogs underwent cardiopulmonary bypass for left ventricular access via atriotomy.
  • A mesh-covered balloon with an electrode array delivered damped sinusoidal electrical discharges.

Related Experiment Videos

  • Standard stimulation techniques were used to assess arrhythmia induction post-ablation (5-8 weeks).

    • Main Results:

    • No ventricular arrhythmias could be induced in any dogs post-ablation.
    • Histological analysis revealed a well-demarcated scar of dense fibrous tissue.
    • Electrophysiology confirmed the absence of action potentials within the scar, with normal function 1 mm away.

    Conclusions:

    • The adapted intraoperative electrical ablation procedure effectively creates an electrophysiologically inert scar.
    • This technique shows promise as a less invasive alternative for treating ventricular arrhythmias.
    • The generated scar demonstrates long-term stability and functional inertness.