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Genomics02:02

Genomics

39.6K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
917
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

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Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
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Next-generation Sequencing03:00

Next-generation Sequencing

97.6K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
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Related Experiment Video

Updated: Jan 10, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

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PRECISION MEDICINE AND ANAESTHESIA: CURRENT CLINICAL AND GENOMICS APPROACHES.

I Nakashidze1, A Nishanthan1, Sh Nakashidze2

  • 11Department of Critical Medicine, Faculty of Natural Sciences and Health Care, Batumi Shota Rustaveli State University, Georgia.

Georgian Medical News
|November 28, 2025
PubMed
Summary

Precision anesthesia leverages pharmacogenomics to tailor treatments, improving patient safety and outcomes. This personalized approach enhances anesthetic effectiveness and reduces adverse drug reactions for better recovery.

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Area of Science:

  • Anesthesiology and Precision Medicine

Background:

  • Anesthesiology is evolving towards more precise, personalized patient care.
  • Pre-operative, intra-operative, and post-operative care are critical for effective pain management and recovery.
  • Coexisting conditions and comorbidities significantly impact anesthetic management and patient outcomes.

Purpose of the Study:

  • To review current clinical and genomic approaches in anesthesia.
  • To highlight the role of pharmacogenomics in personalized anesthesia.
  • To explore emerging technologies transforming precision anesthesia.

Main Methods:

  • Review of current clinical practices in anesthesia.
  • Analysis of the integration of genomic data into anesthetic planning.
  • Exploration of pharmacogenomics' impact on drug metabolism and efficacy.
  • Examination of emerging technologies like AI and nanotechnology in anesthesia.

Main Results:

  • Personalized anesthesia plans, informed by genomic data, enhance anesthetic effectiveness and safety.
  • Pharmacogenomics is pivotal in developing individualized treatment strategies.
  • Identifying genetic markers improves drug metabolism and efficacy, reducing adverse reactions.
  • Emerging technologies promise further transformation in perioperative care.

Conclusions:

  • Anesthesiology is increasingly reliant on precision and personalized approaches for improved patient safety.
  • Pharmacogenomics enables tailored treatment plans based on genetic characteristics.
  • Personalized anesthesia significantly reduces adverse drug reactions and improves therapeutic outcomes, leading to better patient recovery and prognosis.