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Structural basis of improved second-generation 3-nitro-tyrosine tRNA synthetases

Richard B Cooley1, Jessica L Feldman, Camden M Driggers

  • 1Department of Biochemistry and Biophysics, Oregon State University , 2011 Agriculture and Life Sciences Building, Corvallis, Oregon 97331, United States.

Biochemistry
|March 12, 2014
PubMed
Summary

Researchers improved the efficiency of incorporating noncanonical amino acids (ncAAs) like nitrotyrosine into proteins. This advancement in genetic code expansion enhances the study of diseases linked to elevated nitrotyrosine levels.

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