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Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
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Chronic Inflammation: Introduction01:12

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Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
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Chronic Pharyngitis01:23

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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
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Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
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Related Experiment Video

Updated: May 2, 2026

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
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Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis

Published on: December 30, 2025

213

Frontal sinus cholesterol granuloma: Case report.

Nicholas L Deep1, Mohamad R Chaaban, Ajaz L Chaudhry

  • 1Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Allergy & Rhinology (Providence, R.I.)
|March 12, 2014
PubMed
Summary

A rare case of massive cholesterol granuloma in a 15-year-old male

Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Endocrinology

Background:

  • Cholesterol granulomas (CGs) are rare, slowly expanding cystic lesions.
  • Frontal sinus CGs can cause proptosis, diplopia, and orbital masses.
  • Potential contributing factors include chronic nasal obstruction and head trauma.

Purpose of the Study:

  • To report a case of massive frontal sinus cholesterol granuloma in a adolescent.
  • To highlight the endoscopic surgical approach for frontal sinus CGs.

Main Methods:

  • A case report of a 15-year-old male with a massive frontal sinus cholesterol granuloma.
  • Endoscopic sinus surgery was performed for lesion resection.

Main Results:

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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  • Successful endoscopic resection of the massive frontal sinus cholesterol granuloma.
  • Minimally invasive approach with favorable outcomes.

    • Conclusions:

    • Endoscopic sinus surgery is an effective treatment for frontal sinus cholesterol granulomas.
    • This approach offers a minimally invasive option with reduced recurrence rates.