Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

6.5K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.5K
Genomics02:02

Genomics

35.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
35.5K
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

121
Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
121
Pharmacogenetics and Pharmacogenomics: Overview01:29

Pharmacogenetics and Pharmacogenomics: Overview

253
Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...
253
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1.3K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiologists' perspectives on sociocultural and structural factors shaping cardiovascular genetic testing.

medRxiv : the preprint server for health sciences·2026
Same author

COMPREHENSIVE GENETIC INVESTIGATION REVEALS HETEROGENEOUS PATHWAYS TO OBSTRUCTIVE SLEEP APNEA.

medRxiv : the preprint server for health sciences·2026
Same author

Assessing the views and opinions of psychiatric patients receiving genome-guided treatment within the scope of the PREPARE preemptive pharmacogenomics clinical study.

Frontiers in pharmacology·2025
Same author

Genomic medicine year in review: 2025.

American journal of human genetics·2025
Same author

Leveraging genomic biobanks to enhance genetic testing outcomes for kidney disease.

medRxiv : the preprint server for health sciences·2025
Same author

Performance of recommended management among pediatric patients identified through genomic screening.

Translational behavioral medicine·2025
Same journal

Upper Extremity Entrapment Neuropathies in Adults With Arthrogryposis Multiplex Congenita: A National Database Study.

American journal of medical genetics. Part C, Seminars in medical genetics·2026
Same journal

Posthumously Diagnosed Myhre Syndrome Presenting With Pleural Remodeling and Endometrial Cancer.

American journal of medical genetics. Part C, Seminars in medical genetics·2026
Same journal

The International Consortium for Arthrogryposis: A Collaborative Framework for Early Detection, Care, Research, and Education.

American journal of medical genetics. Part C, Seminars in medical genetics·2026
Same journal

Apical Ectodermal Ridge Disruption and Hypoplastic Digits in Amyoplasia.

American journal of medical genetics. Part C, Seminars in medical genetics·2026
Same journal

Caring for Pediatric Clients With Arthrogryposis Multiplex Congenita: The Development of an Occupational Therapy Continuing Education Course.

American journal of medical genetics. Part C, Seminars in medical genetics·2026
Same journal

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway - A Description of Demographic, Medical, and Neurological Findings.

American journal of medical genetics. Part C, Seminars in medical genetics·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

14.0K

Genomic medicine implementation: learning by example.

Marc S Williams

    American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
    |March 12, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Genomic Medicine is emerging in clinical practice. This review covers the Genomic Medicine Working Group, implementation challenges, and ethical considerations for integrating genomic data into healthcare.

    Keywords:
    ethical legal and social issuesfamily historygenomic medicineimplementationpersonalized medicinepharmacogenetics

    More Related Videos

    Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
    11:02

    Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

    Published on: October 18, 2013

    19.0K
    Constructing and Visualizing Models using Mime-based Machine-learning Framework
    06:19

    Constructing and Visualizing Models using Mime-based Machine-learning Framework

    Published on: July 22, 2025

    3.1K

    Related Experiment Videos

    Last Updated: May 2, 2026

    Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
    13:24

    Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

    Published on: April 11, 2016

    14.0K
    Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
    11:02

    Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

    Published on: October 18, 2013

    19.0K
    Constructing and Visualizing Models using Mime-based Machine-learning Framework
    06:19

    Constructing and Visualizing Models using Mime-based Machine-learning Framework

    Published on: July 22, 2025

    3.1K

    Area of Science:

    • Genomics
    • Clinical Practice
    • Healthcare Innovation

    Background:

    • The National Human Genome Research Institute's Genomic Medicine Working Group comprises organizations actively implementing genomic medicine.
    • Implementation examples include family history integration, Mendelian disease programs, pharmacogenomics, and whole exome/genome sequencing.

    Discussion:

    • This article reviews the Genomic Medicine Working Group and provides context for related research.
    • It assesses anticipated provider needs and discusses ethical, legal, and social issues (ELSI) pertinent to genomic medicine implementation.
    • Challenges and potential value of integrating genomic medicine into clinical practice are examined.

    Key Insights:

    • Genomic medicine implementation involves diverse approaches across healthcare organizations.
    • Provider education and addressing ELSI are critical for successful integration.
    • Overcoming implementation challenges is key to realizing the value of genomic medicine.

    Outlook:

    • Continued development and adoption of genomic medicine in clinical settings.
    • Further research into optimizing provider training and patient care pathways.
    • Addressing the evolving ethical, legal, and social implications of widespread genomic data utilization.