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Facilitating Drug Discovery: An Automated High-content Inflammation Assay in Zebrafish
Published on: July 16, 2012
[Zaditen: a pharmacologic and therapeutic profile]
1Division pharmaceutique, Sandoz S.A., Bâle, Suisse.
Abstract:
The pharmacological properties of Zaditen include the inhibition of mediator release, the inhibition of bronchial hyperreactivity and the suppression of beta-adrenergic tachyphylaxis. Its therapeutic efficacy is characterized by a reduction of the severity and the variability of asthma combined with a decrease of bronchodilator use and a progressive improvement of pulmonary function. The normalization of physical activities and sleep disturbances, less absenteeism at work or school, witness a better quality of life. Long term safety and tolerance are excellent.
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