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Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
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Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner

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Tracker Readout ASIC for Proton Computed Tomography Data Acquisition.

Robert P Johnson¹, Joel Dewitt¹, Cole Holcomb¹

¹Santa Cruz Institute for Particle Physics and Physics Department, University of California at Santa Cruz, Santa Cruz, CA 95064 USA.

IEEE Transactions on Nuclear Science

|March 22, 2014

Summary

This summary is machine-generated.

A novel CMOS chip was developed for proton computed tomography (pCT) scanners, enabling rapid data digitization and transmission for high-throughput proton track detection with excellent low-noise performance.

Keywords:

Application specific integrated circuits computed tomography low-noise amplifiers mixed analog digital integrated circuits particle tracking silicon radiation detectors

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Area of Science:

Medical Imaging
Detector Electronics
Particle Physics Instrumentation

Background:

Proton computed tomography (pCT) requires high-performance data acquisition systems.
Existing systems face challenges in handling high data rates from proton track detection.

Purpose of the Study:

To design and validate a unique CMOS chip for the front-end data acquisition system of a pre-clinical pCT scanner.
To meet the demanding requirements of measuring 1-2 million proton tracks per second.

Main Methods:

A custom CMOS chip was designed to handle 64 channels, incorporating logic for control, calibration, triggering, buffering, and zero suppression.
The chip digitizes data and outputs a formatted cluster list for each trigger.
Field-programmable gate arrays (FPGAs) merge lists from multiple chips to construct events for the data acquisition computer.

Main Results:

The chip design was successfully fabricated.
Post-fabrication tests confirmed that the chip meets all performance requirements.
Excellent low-noise performance was demonstrated, crucial for accurate proton track measurement.

Conclusions:

The developed CMOS chip is a key component for advanced pCT data acquisition systems.
The chip's performance validates its suitability for high-rate proton track measurements.
This advancement supports the development of next-generation pre-clinical pCT scanners.