Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neurodegenerative pathologies.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Arterial spin labeling MRI denoising via locally adaptive regularization with structure-guided collaborative data selection.

NeuroImage·2026
Same author

Characterizing the MRI signature of hippocampal sclerosis of aging.

Alzheimer's research & therapy·2026
Same author

An open, fully-processed data resource for studying mood and sleep variability in the developing brain.

Aperture neuro·2026
Same author

Clinicoanatomic localization of iron-rich gliosis in aphasic presentations of globular glial tauopathy.

Brain communications·2026
Same author

Multiple-TE Based Blood-Brain-Barrier Water Exchange Time Measurement Using a TE-Resolved 3D TSE Stack-Of-Spirals Readout.

Magnetic resonance in medicine·2026

Related Experiment Video

Updated: May 1, 2026

Functional Mapping with Simultaneous MEG and EEG
06:04

Functional Mapping with Simultaneous MEG and EEG

Published on: June 14, 2010

17.5K

Brain entropy mapping using fMRI.

Ze Wang1, Yin Li2, Anna Rose Childress2

  • 1Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

Plos One
|March 25, 2014
PubMed
Summary

Brain entropy (BEN) mapping reveals distinct regional networks in the normal brain. This novel approach provides a meaningful measure for understanding brain states and functions.

More Related Videos

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

14.3K
High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
10:06

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

12.2K

Related Experiment Videos

Last Updated: May 1, 2026

Functional Mapping with Simultaneous MEG and EEG
06:04

Functional Mapping with Simultaneous MEG and EEG

Published on: June 14, 2010

17.5K
Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

14.3K
High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
10:06

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

Published on: May 10, 2012

12.2K

Area of Science:

  • Neuroscience
  • Brain Imaging
  • Information Theory

Background:

  • Entropy is fundamental to life and the human brain.
  • Characterizing brain entropy (BEN) can inform assessments of brain states and functions.
  • Limited understanding exists regarding BEN distribution and organization in healthy brains.

Purpose of the Study:

  • To investigate whole-brain entropy patterns in a large cohort of normal subjects.
  • To establish a 3D map of brain entropy distribution.
  • To identify regional BEN networks.

Main Methods:

  • Validation of an approximate entropy measure using synthetic and fMRI data.
  • Analysis of resting-state fMRI data from 1049 multi-site normal subjects.
  • Application of a data-driven clustering method to study spatial heterogeneity.

Main Results:

  • A 3D BEN map demonstrated a distinct low-high entropy contrast between the neocortex and other brain regions.
  • The brain was organized into 7 hierarchical regional BEN networks.
  • These networks align with established structural and functional brain parcellations.

Conclusions:

  • BEN mapping is a reliable measure for assessing brain organization.
  • The identified BEN networks offer insights into brain physiology and function.
  • This study establishes a foundation for using BEN mapping in neuroscience research.