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Related Concept Videos

Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

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Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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Introduction of Intracapsular Rotary-cut Procedures IRCP: A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
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Intrauterine devices: an update.

Julia Hardeman1, Barry D Weiss1

  • 1University of Arizona, Tucson, AZ, USA.

American Family Physician
|April 4, 2014
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Summary
This summary is machine-generated.

Intrauterine devices (IUDs) are safe and effective contraception. Available IUDs include copper and levonorgestrel-releasing options, suitable for various women, including adolescents and breastfeeding individuals.

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Area of Science:

  • Contraception and Family Planning
  • Reproductive Health
  • Gynecology

Background:

  • Three types of intrauterine devices (IUDs) are available in the U.S.: copper T 380A and two levonorgestrel-releasing IUDs (20 mcg/24h and 14 mcg/24h).
  • All IUDs are safe, effective, and primarily work via prefertilization mechanisms.

Purpose of the Study:

  • To review the characteristics, insertion guidelines, and side effect profiles of available intrauterine devices (IUDs).
  • To provide guidance on IUD use in specific populations and circumstances.

Main Methods:

  • Review of prescribing information and current guidelines for available IUDs.
  • Analysis of contraindications, insertion timing, postpartum use, and use in special populations.

Main Results:

  • Copper T 380A can be inserted anytime; levonorgestrel IUDs ideally during the first seven days of menses.
  • Postpartum insertion is possible but associated with higher expulsion rates; a six-week wait is advised after delivery or second-trimester loss for levonorgestrel IUDs.
  • IUDs are suitable for nulliparous women, adolescents, breastfeeding individuals, and those with a history of STIs (after treatment).

Conclusions:

  • IUDs are versatile contraceptive options with specific insertion protocols and considerations for postpartum and STI history.
  • Levonorgestrel IUDs have potential side effects including hormonal effects, while the copper IUD's main side effect is increased menstrual bleeding.