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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
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Intertrigo and secondary skin infections
Monica G Kalra1, Kim E Higgins2, Bruce S Kinney1
1Methodist Health System of Dallas, Dallas, TX, USA.
American Family Physician
|April 4, 2014
Summary
Intertrigo is an inflammatory skin condition caused by moisture and friction in skin folds. It can lead to secondary fungal and bacterial infections, requiring specific topical or oral treatments.
Area of Science:
- Dermatology
- Infectious Diseases
Background:
- Intertrigo is a superficial inflammatory dermatitis affecting opposing skin surfaces.
- It results from moisture, friction, and poor ventilation, exacerbated by bodily secretions.
- Skin folds are prone to erythema, scaling, and breakdown, increasing infection risk.
Purpose of the Study:
- To describe the etiology, clinical presentation, and management of intertrigo and its associated infections.
- To highlight diagnostic methods for differentiating fungal and bacterial superinfections.
- To outline appropriate therapeutic strategies for various causative agents.
Main Methods:
- Clinical examination to identify characteristic erythema and scaling in skin folds.
- Potassium hydroxide (KOH) preparation for suspected candidal infections.
- Bacterial culture and Wood lamp examination for bacterial superinfections.
Main Results:
- Candidal intertrigo often presents with satellite lesions, diagnosable via KOH prep.
- Bacterial superinfections include group A beta-hemolytic streptococcus and Corynebacterium minutissimum.
- Fungal infections respond to topical antifungals; bacterial infections require topical or oral antibiotics.
Conclusions:
- Effective management of intertrigo involves addressing moisture, friction, and ventilation.
- Accurate diagnosis of secondary infections is crucial for targeted therapy.
- Treatment varies from topical antifungals to oral antibiotics based on the identified pathogen.

