Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...

Preventive Healthcare Services

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:

Standards of Care II

Standards of Care II

Nurses bear specific legal responsibilities under several federal statutes, including:

Pharmacogenetics and Pharmacogenomics: Overview

Pharmacogenetics and Pharmacogenomics: Overview

Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...

Evolutionary Psychology

Evolutionary Psychology

Evolutionary psychology explores the origins of human behavior and mental processes by framing them within the context of natural selection, a theory famously propounded by Charles Darwin. This field asserts that many behaviors common across human societies — ranging from instinctive fear reactions to complex social interactions — arose as evolutionary adaptations. These adaptations enhanced the survival and reproductive success of our ancestors, thereby becoming embedded in the...

Standards of Care I

Standards of Care I

Federal statutes profoundly impact nursing practice, providing critical guidelines to ensure patient care is equitable, accessible, and of the highest quality. The following laws address distinct aspects of healthcare provision and patient rights:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Medical Appointments are Associated With Same-Day Worry and Sleep Difficulties Among Cancer Survivors.

Psycho-oncology·2026

Same author

Comparison of In-person Versus Online Comprehensive Pelvic Floor Rehabilitation Program Following Prostatectomy.

Urology·2024

Same author

Grant funding among underrepresented minority and women urologists at academic institutions.

The Canadian journal of urology·2024

Same author

Novel online comprehensive pelvic floor therapy program following prostatectomy.

Translational andrology and urology·2024

Same author

Comparison of In-person FPMRS-directed Pelvic Floor Therapy Program Versus Unsupervised Pelvic Floor Exercises Following Prostatectomy.

Urology·2023

Same author

Editorial Commentary.

Urology practice·2023

Same journal

An Unprecedented Era of Innovation in Non-Muscle-Invasive Bladder Cancer.

The Urologic clinics of North America·2026

Same journal

Hubert Humphrey's Bladder Cancer: If He Could Have Time Traveled, Would that Have Changed the Outcome?

The Urologic clinics of North America·2026

Same journal

Key Clinical Trials Shaping the Future of Superficial High-Risk Bladder Cancer Management.

The Urologic clinics of North America·2026

Same journal

Future Directions: Artificial Intelligence and Digital Tools in Bladder Cancer Care.

The Urologic clinics of North America·2026

Same journal

Economic Considerations in the Management of Superficial Bladder Cancer.

The Urologic clinics of North America·2026

Same journal

Patient-Centered Approaches to Non-Muscle-Invasive Bladder Cancer Care.

The Urologic clinics of North America·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 1, 2026

High Content Screening in Neurodegenerative Diseases

High Content Screening in Neurodegenerative Diseases

Published on: January 6, 2012

Evolution and immediate future of US screening guidelines.

Kirsten L Greene¹, Sanoj Punnen¹, Peter R Carroll¹

¹Department of Urology, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1600 Divisadero Street, A631, San Francisco, CA 94115, USA.

The Urologic Clinics of North America

|April 15, 2014

Summary

This summary is machine-generated.

Clinical trials offer the best evidence for prostate cancer screening guidelines, including age, intervals, and tests. However, overdetection and overtreatment remain concerns, even with active surveillance for low-risk cases.

Keywords:

Guidelines Prostate cancer Prostate specific antigen (PSA)Public health Screening

More Related Videos

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

Real-time Cytotoxicity Assays in Human Whole Blood

Real-time Cytotoxicity Assays in Human Whole Blood

Published on: November 7, 2014

Related Experiment Videos

Last Updated: May 1, 2026

High Content Screening in Neurodegenerative Diseases

High Content Screening in Neurodegenerative Diseases

Published on: January 6, 2012

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

Real-time Cytotoxicity Assays in Human Whole Blood

Real-time Cytotoxicity Assays in Human Whole Blood

Published on: November 7, 2014

Area of Science:

Oncology
Preventive Medicine
Clinical Trials

Background:

Observational studies and simulation models offer insights into prostate cancer screening uncertainties.
Evidence quality varies, with clinical trials considered superior for definitive guidance.

Purpose of the Study:

To highlight the critical role of clinical trials in establishing prostate cancer screening protocols.
To address the challenges of overdetection and overtreatment in prostate cancer screening.

Main Methods:

Review of evidence from well-conducted clinical trials.
Analysis of data regarding screening intervals, age considerations, and diagnostic test combinations.
Evaluation of the impact of overdetection and the role of active surveillance.

Main Results:

Clinical trials provide the strongest evidence for optimizing prostate cancer screening strategies.
Overdetection remains a significant issue, leading to overtreatment in many cases.
Active surveillance is a safe option for a substantial number of men with low-risk prostate cancer.

Conclusions:

High-quality clinical trials are essential for refining prostate cancer screening recommendations.
Balancing the benefits of early detection with the risks of overdetection and overtreatment is crucial.
Active surveillance should be considered as a viable management strategy for appropriate patients.