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Cerebrospinal fluid (CSF) thromboplastic, anticoagulative, and fibrinolytic properties were examined in patients with brain injuries of different etiology (traumas, infarctions, hemorrhages, meningitides or meningoencephalitides), basing on CSF coagulograms. CSF thromboplastic activity and decreased anticoagulative activity were detected in all cases of brain injuries. Increased fibrinolytic activity of CSF correlated well with the lethal outcome in brain damage. The pathogenesis and validity of CSF hemostatic properties in patients with different brain injuries are discussed.
Cerebrospinal fluid (CSF) thromboplastic, anticoagulative, and fibrinolytic properties were examined in patients with brain injuries of different etiology (traumas, infarctions, hemorrhages, meningitides or meningoencephalitides), basing on CSF coagulograms. CSF thromboplastic activity and decreased anticoagulative activity were detected in all cases of brain injuries. Increased fibrinolytic activity of CSF correlated well with the lethal outcome in brain damage. The pathogenesis and validity of CSF hemostatic properties in patients with different brain injuries are discussed.