Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Toxins01:36

Types of Toxins

3.7K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
3.7K
The Periodic Table and Organismal Elements01:27

The Periodic Table and Organismal Elements

18.4K
Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
18.4K
The Periodic Table and Organismal Elements00:57

The Periodic Table and Organismal Elements

161.6K
OverviewElements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally-occurring, and fewer still are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.The Periodic Table Provides Information...
161.6K
Toxic Reactions: Overview01:26

Toxic Reactions: Overview

4.2K
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
4.2K
Drug Toxicity: Dose-Dependent Reactions01:24

Drug Toxicity: Dose-Dependent Reactions

229
Drug toxicities can be stratified into pharmacological, pathological, or genotoxic based on their mechanisms. The incidence and severity of these toxicities generally increase with the drug's concentration in the body and exposure time.Pharmacological toxicity is evident when the therapeutic effects of drugs overshoot into adverse reactions in a predictable, dose-dependent manner. Central nervous system (CNS) depression from barbiturates is a classic example, with effects escalating from...
229
Drug Toxicity: Overview01:00

Drug Toxicity: Overview

295
Drug toxicity quantifies the harm a compound causes to an organism, varying by dose and potentially impacting whole systems or specific organs like the liver. Toxic reactions may arise from venomous insect or spider bites, with effects ranging from mild symptoms to severe outcomes such as brain damage or death. Common forms of acute poisoning include ethanol intoxication and overdose of pain or fever medications, with substances like GHB and heroin being particularly lethal at doses close to...
295

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Central Application Service for Physician Assistants 20-Year Data Report 2002 to 2021.

The journal of physician assistant education : the official journal of the Physician Assistant Education Association·2026
Same author

Risk of COVID-19 infections at the workplace: Lessons learned from OSHA investigations.

Journal of safety research·2026
Same author

Choosing a Primary Care Provider: A Formative Qualitative Study to Identify Patient Preferences.

Journal of patient-centered research and reviews·2026
Same author

Identifying Preferences for Prostate Cancer Screening Among American Indian Men (Project AIMEPCCo): Protocol for a Discrete Choice Experiment.

JMIR research protocols·2026
Same author

Identifying preferences for prostate cancer screening among American Indian men (Project AIMEPCCo): Protocol for a discrete choice experiment.

JMIR research protocols·2026
Same author

What factors influence health professions trainees' preferences for employment in rural Appalachia? a qualitative study to inform the design of a discrete choice experiment.

Medical education online·2026

Related Experiment Video

Updated: May 1, 2026

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
09:33

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium

Published on: December 17, 2018

11.7K

Environmental mercury and its toxic effects.

Kevin M Rice1, Ernest M Walker2, Miaozong Wu1

  • 1Center for Diagnostic Nanosystems, Marshall University, Huntington, WV, USA.

Journal of Preventive Medicine and Public Health = Yebang Uihakhoe Chi
|April 19, 2014
PubMed
Summary

Mercury exposure causes widespread organ damage, affecting the nervous system, cardiovascular, and renal systems. This review details mercury

Keywords:
EnvironmentMercuryToxicity

More Related Videos

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
17:28

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Published on: June 17, 2015

10.8K
Author Spotlight: Investigating the Tolerance of Cabbage Butterflies to Urban Pollutants
08:08

Author Spotlight: Investigating the Tolerance of Cabbage Butterflies to Urban Pollutants

Published on: August 18, 2023

5.8K

Related Experiment Videos

Last Updated: May 1, 2026

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
09:33

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium

Published on: December 17, 2018

11.7K
Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
17:28

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation

Published on: June 17, 2015

10.8K
Author Spotlight: Investigating the Tolerance of Cabbage Butterflies to Urban Pollutants
08:08

Author Spotlight: Investigating the Tolerance of Cabbage Butterflies to Urban Pollutants

Published on: August 18, 2023

5.8K

Area of Science:

  • Environmental Health
  • Toxicology
  • Systemic Pathology

Background:

  • Mercury is a natural and anthropogenic contaminant with long environmental circulation.
  • Human exposure, primarily to methylmercury (MeHg) via contaminated food, leads to toxic effects.
  • Mercury bioaccumulation increases body burden over time.

Purpose of the Study:

  • To review the systemic pathophysiology of mercury poisoning.
  • To detail the toxicological effects of mercury on individual organ systems.

Main Methods:

  • Literature review of mercury toxicology.
  • Analysis of systemic effects across organ systems.

Main Results:

  • Mercury exposure causes cellular, cardiovascular, hematological, pulmonary, renal, immunological, neurological, endocrine, reproductive, and embryonic toxicity.
  • Methylmercury specifically targets the nervous system, impacting adults and developing children.
  • Bioaccumulation of ingested mercury leads to increased body burden.

Conclusions:

  • Mercury poisoning results in multi-systemic organ damage.
  • Understanding mercury's diverse toxicological effects is crucial for public health.
  • Further research into mercury's long-term health impacts is warranted.