Related Experiment Video
Updated: May 1, 2026

Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Published on: December 9, 2022
Targeting sepsis as a performance improvement metric: role of the nurse
Ruth Kleinpell1, Christa A Schorr
1Ruth Kleinpell is Professor, Rush University College of Nursing, and Director of the Center for Clinical Research & Scholarship, Rush University Medical Center, 600 South Paulina Ave, 1062B AAC, Chicago, IL 60612 (ruth_m_kleinpell@rush.edu). Christa A. Schorr is Program Director of Critical Care Clinical Trials at Cooper University Hospital in Camden, New Jersey, and is Nurse Leader for the design and implementation for the Surviving Sepsis Campaign database.
Abstract:
Sepsis is the body's systemic response to infection that can be complicated by acute organ dysfunction and is associated with high mortality rates and adverse outcomes for acute and critically ill patients. The 2012 Surviving Sepsis Campaign guidelines advocated for implementation of evidence-based practice care for sepsis, with a focus on quality improvement. Nurses are directly involved in identification and management of sepsis. Implementing performance improvement strategies aimed at early recognition and targeted treatment can further improve sepsis care and patient outcomes. This article presents an overview of the process of implementing performance improvement initiatives for sepsis care, highlighting the significant contribution of nursing care.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Endocarditis IV: Nursing Management
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Angina V: Nursing Management
Pericarditis IV: Nursing Management
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...

