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Updated: Apr 30, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Dose distribution outside the target volume for 170-MeV proton beam
K Pachnerová Brabcová1, I Ambrožová2, J Kubančák3
1Department of Applied Physics, Chalmers University of Technology, Fysikgården 4, Göteborg SE-412 96, Sweden Department of Radiation Dosimetry, Nuclear Physics Institute of the ASCR, Na Truhlářce 39/64, 180 00 Prague, Czech Republic brabcova@chalmers.se.
Abstract:
Dose delivered outside the proton field during radiotherapy can potentially lead to secondary cancer development. Measurements with a 170-MeV proton beam were performed with passive detectors (track etched detectors and thermoluminescence dosemeters) in three different depths along the Bragg curve. The measurement showed an uneven decrease of the dose outside of the beam field with local enhancements. The major contribution to the delivered dose is due to high-energy protons with linear energy transfer (LET) up to 10 keV µm(-1). However, both measurement and preliminary Monte Carlo calculation also confirmed the presence of particles with higher LET.

