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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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Postradiation hypertrichosis: a paradox
Jai Prakash Agarwal1, Maheshkumar N Upasani, Yogesh Ghadi
1Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
Journal of Cancer Research and Therapeutics
|April 26, 2014
Summary
Radiation therapy typically causes hair loss (alopecia). This study details a rare case of excessive hair growth (paradoxical hypertrichosis) occurring within radiation treatment areas after successful lung cancer therapy.
Area of Science:
- Oncology
- Radiation Oncology
- Dermatology
Background:
- Radiotherapy is a standard treatment for non-small cell lung cancer.
- Radiation-induced alopecia is a well-documented side effect of radiotherapy.
Observation:
- A patient with stage IIIB non-small cell lung adenocarcinoma received radiochemotherapy.
- The patient achieved a complete response to the treatment.
Findings:
- An unusual late effect of radiation was observed: paradoxical hypertrichosis.
- Excessive hair growth occurred specifically within the radiation portals.
Implications:
- This case highlights an unexpected biological response to radiation therapy.
- Further research is needed to understand the mechanisms behind radiation-induced hypertrichosis.
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