[Simultaneous study of bile excretion and secretory ability of the stomach using pentagastrin]

The author has examined the possibility of a simultaneous combined examination of liver exosecretion and gastric secretion. A two-channel gastroduodenal tube has been employed. The findings evidence that pentagastrin (6 micrograms/kg) stimulation during the third phase of bile excretion potentiates the effects of cholecystokinetics administered in succession: 33% magnesium sulfate solution (0.5 ml/kg) and, after C bile is obtained (the fifth phase), olive oil (0.4 ml/kg). Continuous aspiration of the gastric juice prevents pancreatic stimulation and permits the measurements of gastric acid production and of the bile debit. In contrast to normal subjects, the 24 examinees with chronic gastritis often presented with an increased volume of the residual B bile (the IVA phase), this evidencing the gall-bladder hypotonia. The 14 patients with inadequate gastric secretion have developed dyskinesias of the gall-bladder and bile ducts twice more often than the rest patients. The suggested method helps detect combined abnormalities of the stomach and the biliary system; it is satisfactorily tolerated by the patients.